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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC63 All Species: 13.94
Human Site: S540 Identified Species: 25.56
UniProt: Q8NA47 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NA47 NP_689804.1 563 66250 S540 Y I L K E N R S K E V R G D S
Chimpanzee Pan troglodytes XP_509370 563 66213 S540 Y I L K E N R S K E V R G D S
Rhesus Macaque Macaca mulatta XP_001100621 223 26551 R201 N V Y Q Q L Q R C L L M Q K K
Dog Lupus familis XP_534677 558 65244 S535 V L S N Q L R S R E L H S D S
Cat Felis silvestris
Mouse Mus musculus Q8CDV6 558 65255 T536 N F L Q R E R T K E L Q D T M
Rat Rattus norvegicus Q4V8F7 559 66089 W537 V A S G S W S W R T T F R R N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506125 545 64339 D523 L N D K H Y K D Y F L E K S D
Chicken Gallus gallus XP_415165 550 63725 L527 A Q L R E L L L S K Y Q K E Q
Frog Xenopus laevis NP_001083612 559 64752 K534 R I M K G V L K K E Q K A T R
Zebra Danio Brachydanio rerio NP_001007409 566 66367 S539 S V L H K D E S L R V G G G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394326 522 61249 S499 Q R L D E D Y S E L L H N I S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789929 570 65774 A540 V L K R E E A A K K K G F Q Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C9Z8 235 26834 V213 T L D A R L D V A F R Q K L P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 37.1 76.3 N.A. 72.1 70.8 N.A. 56.1 43.8 29.3 28.2 N.A. N.A. 25.3 N.A. 29.4
Protein Similarity: 100 99.6 38.5 88 N.A. 87.5 83.4 N.A. 73.5 66.7 52.9 53.5 N.A. N.A. 47.4 N.A. 51.7
P-Site Identity: 100 100 0 33.3 N.A. 26.6 0 N.A. 6.6 13.3 26.6 26.6 N.A. N.A. 26.6 N.A. 13.3
P-Site Similarity: 100 100 33.3 60 N.A. 53.3 13.3 N.A. 20 40 40 46.6 N.A. N.A. 46.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. 21.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 30.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 0 0 8 8 8 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 16 8 0 16 8 8 0 0 0 0 8 24 8 % D
% Glu: 0 0 0 0 39 16 8 0 8 39 0 8 0 8 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 16 0 8 8 0 0 % F
% Gly: 0 0 0 8 8 0 0 0 0 0 0 16 24 8 0 % G
% His: 0 0 0 8 8 0 0 0 0 0 0 16 0 0 0 % H
% Ile: 0 24 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 8 31 8 0 8 8 39 16 8 8 24 8 16 % K
% Leu: 8 24 47 0 0 31 16 8 8 16 39 0 0 8 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 8 % M
% Asn: 16 8 0 8 0 16 0 0 0 0 0 0 8 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 8 8 0 16 16 0 8 0 0 0 8 24 8 8 8 % Q
% Arg: 8 8 0 16 16 0 31 8 16 8 8 16 8 8 8 % R
% Ser: 8 0 16 0 8 0 8 39 8 0 0 0 8 8 31 % S
% Thr: 8 0 0 0 0 0 0 8 0 8 8 0 0 16 0 % T
% Val: 24 16 0 0 0 8 0 8 0 0 24 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % W
% Tyr: 16 0 8 0 0 8 8 0 8 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _